BPC157 Peptides for Sports Injury Repair
BPC157 Peptide for Injury Repair also called Body Protection Compound or Bepecin. A pentadecapeptide made up of 15 amino acids discovered in human gastric juice. It has been seen to accelerate the healing of injuries- Including gastric ulcers, tendons, ligaments & bones in testing. BPC-157 activates the proteinic FAK-paxillin pathway. Induces F-actin formation in fibroblasts. Increases the probability of cell survival during oxidative stress. BPC-157 is currently in phase II clinical trials for the treatment of IBD.
Our Experience: (Sports Medicine & Tendon/Ligament Repair)
The safety profile seems good, we have not had any allergic reactions so far. The injections seem to be the most potent when including the absorption ratios into the equation. We inject 200-300mcg via subcutaneous injection as close to the site of injury as possible. Studies have found that the patients who address the injuries (ligament/tendon/muscle tears) as early as possible see the best recovery mitigation. MedClub recently treated an (IT) tear in Dr. Jenn’s left knee with Platelet Rich Plasma, allowed the inflammation response to occur over 10 days, then started BPC-157 twice daily. An injury that would have taken multiple months to heal, ended up healing in less than 1 month. Tendon ends start to die quickly in post tear situations so quick action is key. BPC-157 is not effective when healing fully torn ligaments/tendons, but aids the recovery time after surgical intervention. This also leads us to believe that this peptide could really benefit people undergoing physical therapy, or in the recovery phase of certain injuries. MedClub® is helping patients gain access for an affordable price. We highly recommend the use of PRP before starting the BPC, as this combination/timeline of care has yielded the most promising results.
BPC-157 is commonly used to repair tendons, ligaments, muscles, ulcers, & organ damage. Commonly prescribed with anti-inflammatories. The current research suggests Bepecin influences multiple growth factors commonly involved in angiogenesis (production of blood vessels, platelets) as well as other factors involved in regeneration following damage. Our first hand experience with this peptide has been promising, showing 50-100% faster healing after injury. The current research has only been studied on rat populations, and much more is necessary to determine the exact methods of action pertaining to this peptide. BPC 157 may serve as a novel mediator of Robert’s cytoprotection, involved in maintaining of GI mucosa integrity, with no toxic effect. BPC 157 was successful in the therapy of GI tract, periodontitis, liver and pancreas lesions, and in the healing of various tissues and wounds. (Stimulated Egr-1 gene, NAB2, FAK-paxillin and JAK-2 pathways)
ORAL: 250-500 mcg by mouth daily in 1-2 divided doses
SUBQ: 250-500mcg subcutaneously once-twice daily
INTRAMUSCULAR: 250-500mcg as close to the site of injury as possible QD-BID
SUBLINGUAL: 200-500 mcg between cheek and gum daily in 1-2 divided doses
BPC-157 used to treat injuries
We will use the ACL tendon in the knee as an example for this article. This article is for educational purposes only, and this is not medical advice. We recommend patients come in person to receive proper diagnosis and training.
We have noticed that the subcutaneous injections of BPC-157 work best when injected as close to the site of injury as possible. For an IT tear, ACL/MCL the patient would draw up 200mcg into an insulin syringe and inject as close to the tendon as possible twice per day, usually in the morning and evening time. Physical therapy during this period is crucial, as well as light stretching after the initial inflammatory period has subsided. Most patients notice an aching sensation almost immediately, this is normal. Patients notice a difference in about 1-2 weeks, but 4 weeks is the recommended therapy duration. This is very injury specific, partial tears have higher success rates then complete tears. A full tear typically requires surgical intervention since the ends of the tendon start to die almost immediately. A surgeon would then snip off the ends to expose and connect the healthier tissue. For partial tears, or minor fractures BPC-157 has had very promising results & is getting athletes back to their sport in about half the time.
Combining BPC-157 with other therapies or medications
BPC157 Peptides for Injury Repair are effective, but a combination of therapies works best. We typically start with a diagnosis at our clinic, then assess the success ratio for each patient. This gives a clear path as to which therapies will benefit patients most, and also allows us to plot a timeline based on lifestyle. i.e. someone who is very active and suffers a ligament tear will benefit most from an initial round of PRP as soon as possible after the initial injury. Then we will allow the PRP some time to work before starting them on a course of BPC-157 injections. We will also utilize low dose Oxandralone orally around week 3 or 4 to help the patient maintain muscle mass and stop any atrophy. This combination is paired with a nutrient dense diet, fluids, electrolytes, & supplementation to make sure the body has more than it needs to undergo this process.
The body is an amazing organism, able to assess, process, and restore damaged cells all on its own. The goal is to optimize the body’s cellular repair process while decreasing duration.